
The Pilgrims' first-ever foray into the Midland Youth Cup sees the Red Imps provide the opposition, with a further group game against Chesterfield to unfold in November.
Charley Sanders and Jordan Nuttell are expected to lead United's attack as they seek to bolster their first team chances over the coming weeks.
Keeper Sam Vince should be fit to return after a groin injury.
Admission to the Fantasy Island Stand is available, priced £3 for adults and £2 for concessions.
United (from): Benton, Vince, Andriulionis, Briers, Delahoy, Devlin, Eyett, Kormis, McKue, Melville, Nuttell, Revell, Sanders, Sowerby, Spencer, Squire.