In addition to contesting Football Conference Youth Alliance and FA Youth Cup action, the Pilgrims will enter the Midland Youth Cup in pursuit of silverware.
United will play two group fixtures — away at Chesterfield and at home to Lincoln City — with the group winners progressing to the semi-final stage alongside three other regional qualifiers.
All group matches must be concluded by November 30.
EAST GROUP 1
EAST GROUP 2
WEST GROUP 1
WEST GROUP 2