Jack Friend fired the Pilgrims into an 11th minute lead, only for goals from Mitch Husbands and Charlie Dawes to turn the tide in Worksop's favour. Jamie McGhee restored parity in the 50th minute.
United included under-21s players Jason Alexander and Jai Lyons from the start, alongside youth team full-back Jack McCallum and trialist Kingsley Ogbodo.
Boston (4-4-2): Jason Alexander; Jai Lyons (Grant Roberts 58), Zak Mills (Mark Jones 42), Carl Piergianni, Jack McCallum; Jake Sheridan (Kaine Felix 46), Kingsley Ogbodo (Kyle Dixon 58), Jamie McGhee (Harry Limb 70), Jay Rollins (Jordan Deacey 58); Jack Friend, Cameron Johnson (Dayle Southwell 58).
Referee: Chris Ward.
PIC: Chris Etchells.