Following a blank weekend due to Spennymoor Town's ongoing pitch problems, United will be looking for their maiden victory when the Brakes come to town (kick-off 7.45pm).
The Pilgrims have drawn both matches 1-1 so far, against Chester FC and Alfreton Town, and Craig Elliott's side will now be looking for their first three-point haul, following Jake Wright's second half equaliser last time out.
Striker Dominic Knowles is expected to be involved competitively for the first time following a pre-season calf injury, but Elliott will check on the fitness of midfielder Andi Thanoj, who limped out of the Alfreton encounter with his own calf strain.
Karl Byrne and Tom Clare are available for selection too, but Jonathan Wafula (knee) is still ruled out.
Leamington have gleaned five points from their opening three fixtures, with draws against Kidderminster Harriers (2-2) and Curzon Ashton (1-1) sandwiching a 2-0 home win over Brackley Town.
Last season's corresponding fixture ended 1-1, with Ben Davies on target from the penalty spot for the Pilgrims.
Tuesday's match referee is Dean Watson, who last officiated United against Altrincham in January.
Matchday updates for those not in attendance will be published on Twitter via @bostonunited — starting with team news at 6.45pm.
Ticket Office: 9.00am
Pilgrim Lounge: 6.00pm
Club 85 and Cropleys Lounge: 6.00pm
Club Shop: 6.30pm
50/50 Draw: £1
BUSA Golden Goal: £1
Academy Teamsheet Raffle: £1