
The Pilgrims head to Ashby Avenue (kick-off 7.45pm), following their penalty shootout victory over Grimsby Borough in November.
Jamie Raynor's under-23s will provide the basis of United's squad, although there could be a sprinkling of senior involvement as new manager Paul Hurst contemplates game time for some fringe players.
Billy Bradley will be among the United players on show - having just completed a loan spell with Wednesday's opponents.
Admission prices have been set at £9 for adults, £6 for concessions and £3 for under-16s.
PIC: Chris Bray.