The Pilgrims travel to Long Eaton United (kick-off 7.45pm) in the first qualifying round encounter at Grange Park.
United youth team supremo Lee Mitchell will shuffle his pack, with third year duo Harry Cranfield and Jamie Gaukroger ineligible, while Lewis Bontoft serves the second of a three-match suspension.
Should the scores be level after 90 minutes, extra-time and potentially penalties will be utilised to determine who reaches the second qualifying round.